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Qian (George) Li

Coordinator: Herbal Medicines Research and Education Centre, Academic (Research).

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Qualifications

BSc, MSc, PhD Zhongshan(Sun Yat-sen), MRACI

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Contact Details

University of Sydney
Phone: +61 2 9351 4435
Fax: +61 2 9351 8638
Email:
Room N411
Pharmacy Building A15
The University of Sydney
NSW 2006 Australia

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Research Interests

  • Mechanism of action and active components of popular herbal medicines for management of diabetics.

    Immunomodulation and active components of popular herbal medicines for cancer management.
  • Pharmacognosy standardization, characterization, quantitative analysis of herbal medicines such as Echinacea, and propolis with HPTLC and HPLC.
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Selected recent publications

  • Roufogalis BD, Duke CC, Li Q (1998): Use of natural products and related synthetic compounds for the treatment of cardiovascular diseases. United States Patent, Patent Number 5741821, April 21, 1998.
  • Roufogalis BD, Li Q, Tran VH, Kable, EPW, and Duke CC (1999): Investigation of plant derived phenolic compounds as plasma membrane Ca2+-ATPase inhibitors with potential cardiovascular activity. Drug Devlop. Res. 3-4, 235-249.
  • Li Q, Duke CC, Roufogalis BD. The Progress of Chinese Medicine in Australia, chapter in The Way Forward for Chinese Medicine, P 173 to 190. Kelvin Chan and Henry Lee, 2002, Taylor & Francis.
  • George Q Li, Colin C Duke, and Basil D Roufogalis, The Quality and Safety of Traditional Chinese Medicines, Australian Prescriber 2003 Vol 26 No6, p128-130.
  • Yuhao Li, Gang Peng, Qian Li, Suping Wen, Tom Hsun-Wei Huang, Basil D Roufogalis, Johji Yamahara, Salacia oblonga Improves Cardiac Fibrosis and Inhibits Postprandial Hyperglycemia in Obese Zucker Rats, Life Sciences 2004, 75:1735-1746.
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Statement of Record

  • Undergraduate and postgraduate studies and research in Botany. Research conducted at Zhongshan (Sun Yat-sen) University includes taxonomy of Clauseneae, anatomy of Tsugo-Keteleeria longibracteata and ecological effects of Farmland Forest Net on production of rice.
  • Chemistry and quantitative analysis of medicinal plants. Isolation, identification of alkaloids, coumarins, and essential oils in Murray, Clausena, Micormelum of Clauseneae (Rutaceae), Quantitative analysis of indole alkaloid yuehchukene in Murraya species at Zhongshan University, Chinese University of Hong Kong and the University of Sydney under supervision of Prof HT Chang and YC Kong; Carried out clinical research on the pharmacokinetics of the anti-rheumatoid arthritis drug hydroxychloroquine mainly involving in the quantitative analysis and enantiomer separation of the drug in humane fluids with HPLC.
  • Chemistry and bioactive substances from medicinal plants. Carried out study for new Ca2+-ATPase inhibitors from natural and synthetic compounds as potential agents for the treatment of cardiovascular diseases with Prof B Roufogalis and Dr CC Duke. Long chain alkyl phenols which act at enzyme, cellular and organ levels were isolated and identified from Grevillea robusta and granted US patent.
  • Chemical profile and fingerprint, bioactive substances from herbal medicines, Working with Prof B Roufogalis, Dr CC Duke, Dr YH Li. Research and development of Gynostemma pentaphyllum for management of hyperlipidemia; Mechanism of action and active components of herbal medicines including Punica granatum, Salacia oblonga for management of diabetics; Pharmacognosy standardization, quality analysis with HPTLC and HPLC of herbal medicines such as Echinacea sp, Panax ginseng, Aristolochia, Ginkgo biloba, and propolis.
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