Dr Romano Fois

Lecturer, Faculty of Pharmacy.

Qualifications

BPharm PhD

Contact Details

University of Sydney
Phone: +61 2 9351 4434
Fax: +61 2 9351 4391
Email:
Room 414
Badham Building A16
The University of Sydney
NSW 2006 Australia

Research Interests

  • Clinical pharmacokinetics and therapeutic drug monitoring.
  • Epidemiological approaches to managing adverse-drug-reaction data.
  • Systems approaches to quality and safety in medication use and quality in dispensing and extemporaneous compounding by pharmacists.

Possible Advanced Projects in 2007 include:

  1. ADR Monitoring: We are currently analysing a large Australian database of reported adverse drug reactions (ADRs). The approach involves developing and testing models relating known pharmacokinetic parameters of drugs to types of adverse events reported. The objective is to identify important drugs and highlight associated parameters (which have their roots in pharmacokinetics) to address in individualising therapy for patients based on what is known about their particular parameters. This project involves analysing and interpreting data and proposing and testing hypotheses. Advanced students interested in pharmacoepidemiology would find this project interesting.
  2. A Systems approach to signalling issues of Quality and Safety of medication use in Australia: We are currently developing proposals for collecting and analysing incident reports of poor quality use of medicines (QUM) and harm (actual or potential) to patients associated with medication use in Australia. The project is seeking to develop a prospective, systems-based approach to signalling and addressing deficiencies in pharmacotherapeutic systems (i.e. the health system) in the Australian environment. This project involves developing methods for data collection, management and analysis. Concepts of root-cause analysis would be developed and implemented. The project could target a specific suspected area of poor QUM. This would involve reviewing the literature around quality and safety incident reporting, designing the data collection instrument and through collaboration with a small number of sentinel pharmacies, implementing and testing a process of data collection and root cause analysis. Advanced students with an interest in pharmacoepidemiology, public health and system safety would find this project interesting.