Research
Book Chapter
2008
"Current methods in the isolation and characterisation of saponins from Gynostemma pentaphyllum" "Current Trends in Phytochemistry". 2008:283-309 ISBN 978-81-308-0277-0. Valentina Razmovski-Naumovski, George Q. Li, Rujee K. Duke, Bruce N. Tattam, Basil D. Roufogalis, Colin C. Duke*
Publications
2009
High performance liquid chromatography assays for desmethoxyyangonin, methysticin, kavain and their microsomal metabolites Shuang Fu, Bruce N. Tattam, Colin C. Duke, Iqbal Ramzan Biomedical Chromatogr, 2009; Jan 23:81-91
Synthesis and NMR characterization of methyl esters of eicosapentanenoic acid monoepoxides. Pei H. Cui, Wei V Zhang,James Hook, Bruce N Tattam, Colin C. Duke, Michael Murray.Chemistry and Physics of Lipids 159 (2009) 30-37
A high-throughput liquid chromatography/tandem mass spectrometry for simultaneous in vivo phenotyping of five major cytochrome P450 enzymes in patients. Ghassabian Sussan, Chetty Manoranjenni, Tattam Bruce N, Glen John, Rahme Jeannie, Stankovic Zvijezdana, Iqbal Ramzan, Murray Michael, & McLachlan, Andrew. Therapeutic Drug Monitoring: Volume 31(2) April 2009 pp239-246
The reliability of reports of recent psychoactive substance use at the time of admission to an acute mental health unit. Rhoderic K Chung, Matthew M Large , Graham A Starmer, Bruce N Tattam,Michael B Paton and Olav B Nielssen . Accepted for publication in J Dual Diagnosis. 20/11/08
2008
Monoepoxy octadecadienoates and monoepoxy octadecatrienoates 2: Mass spectral characterization. Pei H. Cui, Rujee K. Duke, Bruce N Tattam, Colin C. Duke Journal of Chemistry and Physics of Lipids 152(2008) 65-70
A High throughput assay for Irinotecan(CTP-11) and its two major metabolites using liquid chromatography/tandem mass spectrometry. D’Esposito Fabrizio, Tattam Bruce N, Ramzan Iqbal, Murray Michael. Journal of Chromatography B, 875 (2008) 522-530
Stability of omeprazole suspension; implications for paediatric prescribing. Linda Velta Graudins, Naghmeh Jabarizadeh Kivi, Bruce N Tattam . Journal of Pharmacy Practice and Research Volume 38, No4,2008 276-279.
2007
Plasma Distribution and its Impact on Pharmacokinetics Liposomal Amphotericin B in Paediatric Patients with Malignant Diseases. Ying Hong,1 Peter J. Shaw,2 Bruce N. Tattam,1 Christa E. Nath,3 John W. Earl,3 and Andrew J. McLachlan1* . European Journal of Clinical Pharmacology . Feb (2007) 63: 165-172
2006
Phytoestrogens and Indicators of Breast Cancer Survival. Tam C Ha, Philippa M Lyons-Wall, Douglas E.Moore, Bruce N Tattam, John Boyages, Owan A Ung & Richard J Taylor. Dec (2006). Nutrition and Cancer Vol 56 No1 Pages 3-10
2002
In Vitro Distribution and Protein Binding of Tacrolimus In Human Blood. H.Zahir, RA Nand, KF Brown, BN Tattam & AJ McLachlan Journal of Pharmacological and Toxicological Methods Volume 46, Issue 1, pp.27-35 [Abstract]
2001
Routine Gas Chromatographic Determination of Diakylphosphate Metabolites in the Urine of Workers Occupationally Exposed to Organophpsphorus Insecticides. A.N. Oglobline , G.E. O'Donnell, R.Geyer, G.M.Holder and B. Tattam . Journal of Analytical Toxicology ISSN 0146-4760, Volume 25, Number 3, April 2001, pp. 153-157. [Abstract]
Negative Ion Chemical Ionization GC/MS-MS Analysis of Diakylphosphate Metabolites of Organophosphate Pesticides in Urine of Non- occupationally Exposed Subjects. A.N. Oglobline , Helen Elimelakh, B. Tattam ,G.E. O'Donnell, R.Geyer, G.M.Holder. Analyst, 2001, 126(7), 1037 - 1041. [Abstract]
Quantification of epimeric budesonide and fluticasone propionate in human plasma by liquid chromatography atmospheric pressure chemical ionization tandem mass spectrometry. Benny Li, Bruce Tattam, Kenneth F Brown, Paul J. Seale. Journal of Chromatography B Vol 761/2, pp 177-185 [Article]
2000
Pharmacokinetics of epimeric budesonide and fluticasone propionate after repeat dose inhalation - intersubject variability in systemic absorption from the lung [Pharmacodynamics] Minto, Charles; Li, Benny *; Tattam, Bruce; Brown, Ken; Seale, J. Paul; Donnelly, Richard British Journal of Clinical Pharmacology, Volume 50(2),August 2000, pp 116-124.
1999
The Effects of Ephedrine on the Development of Fatigue in a Prolonged Driving-Related Task. M.Moolenaar, P.A. Desmond, D.J. Mascord, G.A. Starmer and B.Tattam Hum. Psychopharmacol. Clin. Exp. 14, 415-427 (1999). [Article]
Photodegradation of amiloride in aqueous solution. Yuan Nian Benny Li, Douglas E. Moore* , Bruce N. Tattam International Journal of Pharmaceutics 183 (1999) 109-116. [Article]
1998
Degradation Products of Beclomethasone Dipropionate in Human Plasma. Kuncoro Foe, Andrew Cheung, Bruce Tattam, Kenneth F Brown and John P Seale. Drug Metabolism and Disposition Vol.26,Issue 2,132-137 February 1998. [Article]
Dramatic changes in oxidative tryptophan metabolism along the kynurenine pathway in experimental cerebral and non-cerebral malaria Latifu A.Sanni, Shane R. Thomas, Bruce N Tattam, Douglas E Moore, Geeta Chaudhri, Roland Stocker and Nicholas H Hunt. American Journal of Pathology Vol 152 No2 611-619 (Feb 1998) [Abstract]
1997
A sensitive method for quantification of Fluticasone Propionate in Human Plasma by High Performance Liquid Chromatography / Atmospheric Pressure Chemical Ionization Mass Spectrometry. Benny Li, Bruce Tattam, Kenneth F Brown, Paul J. Seale. Journal of Pharmaceutical and Biomedical Analysis. Vol 16, (1997) 447-452 [Article]
Kynurenine pathway inhibition with 6-chloro-D-tryptophan reduces neurotoxicity of HIV-1 infected macrophage supernatants. S.J. Kerr, P.J. Armati, L.A. Pemberton, G. Smythe, B. Tattam & B.J Brew. Neurology 1997; 49:1671-1681 [Abstract]
1996
Determination of epimers 22R and 22S of Budesonide in human plasma by High Performance Liquid Chromatography / Atmospheric Pressure Chemical Ionization Mass Spectrometry. Benny Li, Bruce Tattam, Kenneth F Brown, Paul J. Seale. Journal of Chromatography B:Biomedical Applications. Vol 683, No 2 p259-268, 1996. [Article]
Pre-1995
Preparation of Hydrofullerenes by Hydrogen Radical Induced Hydrogenation. Attalla, M.I. ; Vassallo, A.M. ; Tattam, B.N. ; Hanna, J.V.; Journal of Physical Chemistry v97 n24 Jun 17 1993 p 6329-6331.
Effects of Psychoactive Drugs on Car Driving Performance: Drugs in Crash Involved Drivers. G.A. Starmer,D Cairns,D.J. Mascord,J. Perl,B. Tattam,J. Vine,T.R. Watson. Clin Neuropharm., Vol 15 , Suppl. 1 Pt. A, 1992 p598A-600A.
Lipid profile of Pleurotus Sajor Caju. N.G.Nair,C.H.Song,J.Y.Jiang,J.Vine,B.Tattam and K.J.Cho. Ann of Applied Biology, Vol 114 p167-176 1989.
Ammonia and Methane Chemical Ionization Mass Spectra of Methotrexate and its Amide and Ester Analogs.
H.T.A Cheung, B.N.Tattam, D J.Antonjuk, D.Boadle. Biomedical Mass Spectrometry, Vol.12.No1, 1985.
Conference Presentations
2000
S Ghassabian, B Tattam, I Ramzan, M Murray and M Chetty. A simplified liquid chromatography/tandem mass spectrometry assay for the simultaneous assessment of cytochrome P450 1A2, 3A4, 2C9, 2C19 and 2D6 activities.
Australasian Pharmaceutical Sciences Association meeting, Adelaide, SA, Dec 3-5, 2006.
F D'Esposito, B Tattam, I Ramzan and M Murray. Development of a high throughput LC/MS/MS method for the determination of the anticancer agent irinotecan and its two major metabolites. Australian Health and Medical Research Congress combined meeting of societies, Melbourne, VIC, Nov 27-Dec 1, 2006. In Proceedings of The Australasian Society of Clinical and
Experimental Pharmacologists and Toxicologists.
S Ghassabian, B Tattam, I Ramzan, M Murray and M Chetty. A simplified liquid chromatography/tandem mass spectrometry assay for the simultaneous assessment of cytochrome P450 1A2, 3A4, 2C9, 2C19 and 2D6 activities with a new cocktail. American Association of Pharmaceutical Scientists meeting, San Diego, CA, USA, Nov 11-15, 2007.
N Nebot, F D’Esposito, B Tattam, V Zhang, S Crettol, K Li and M Murray. Involvement of CYP2C8 in the oxidative biotransformation of imatinib. 7th Southwestern P450 meeting, Camp Allen, Navasota, TX, USA May 12-14, 2008.
F D’Esposito, BN Tattam, I Ramzan, RJ Edwards and M Murray. Cytochrome P450 3A4-dependent biotransformation of the anticancer agent irinotecan is impaired in chronic liver disease. 7th Southwestern P450 meeting, Camp Allen, Navasota, TX, USA May 12-14, 2008.
N Nebot, F D’Esposito, B Tattam, V Zhang, S Crettol, K Li and M Murray. Involvement of CYP2C8 in the oxidative biotransformation of imatinib. International Society for the Study of Xenobiotics, 10th European Regional Meeting. Vienna, Austria May 18-21, 2008.
F D’Esposito, BN Tattam, I Ramzan, RJ Edwards and M Murray. Cytochrome P450
3A4-dependent biotransformation of the anticancer agent irinotecan is impaired in chronic liver disease. ESF-UB Conference in Biomedicine: Pharmacogenetics And Pharmacogenomics: Adverse Drug Reactions. Hotel Eden Roc, Sant Feliu de Guixols, Spain, June 27- July 2, 2008.
S Crettol, N Nebot, F D’Esposito, B Tattam and M Murray. Inhibition of human drug metabolizing cytochromes P450 by the tyrosine kinase inhibitor imatinib. Australian Health and Medical Research Congress combined meeting of societies, Brisbane, QLD, Nov 18-21, 2008. In Proceedings of The Australasian Society of Clinical and Experimental Pharmacologists and
Toxicologists.
Fluticasone Propionate Metabolism In Rat Liver. Kim. L, McLachlan AJ, Tattam B N and Ramzan I. Presented at the Australasian Pharmaceutical Science Association ( APSA ). Newcastle NSW, Australia 6th - 8th December 2000 O-59
Determination of Succinylcholine In Human Plasma. Garlapati V, Ramzan I, Tattam B N and Tran,V H. Presented at the Australasian Pharmaceutical Science Association ( APSA ) Newcastle NSW, Australia 6th - 8th December 2000 O-64
1999
Analysis of Inhaled Glucocorticosteroids - Epimeric Budesonide and Fluticasone Propionate in Human Plasma by Liquid Chromatography Atmospheric Pressure Chemical Ionization Tandem Mass Spectrometry (LC/APCI/MS/MS)
Yuan N (Benny) Li ,Bruce Tattam , Kenneth. F. Brown And John. P. Seale. Presented at the 17th Australian and New Zealand Society for Mass Spectrometry Conference (ANZSMS 17) Thredbo Alpine Village, 31st January to 4th February, 1999. TuO-07
1997
The analysis of Quinolinic in Mice Brain by Negative Ion Chemical Ionisation Gas Chromatography Mass Spectrometry / Mass Spectrometry (GCMS/MS) using selected reaction monitoring.
Bruce Tattam, Victor Awad, Douglas Moore Latifu Sanni and Nicholas Hunt. Presented at the 16th Conference of the Australian and New Zealand Society for Mass Spectrometry. (ANZSMS) February 3 to 6 1997 Hobart, University of Tasmania. MoO-19
Drug usage by Australian Drivers G.A.Starmer, T.Bock, J.Harris, D.J.Mascord, J.Nelson, B.Tattam & R.Zeleny Presented at the 14th International Conference on Alcohol, Drugs and Traffic Safety / ICADTS Annecy - 21/09/97 - 26/09/97
Plasma Concentration Profiles of Inhaled Epimeric Budesonide and Fluticasone Propionate in healthy subjects Benny Li, Bruce Tattam, Kenneth F Brown, Paul J. Seale. Presented at the Australasian Pharmaceutical Science Association ( APSA ) Sydney Australia December 1997. P35 O-13
1996
Dramatic changes in oxidative Tryptophan metabolism along the Kynurenine pathway in cerebral and non cerebral murine malaria. Latifu A Sanni , Shane R. Thomas , Bruce Tattam, Douglas Moore Roland Stocker, Nicholas H Hunt. Presented at the Australian Society for Medical Research (ASMR) conference Sydney June 5, 1996.
A sensitive method for the quantification of Fluticasone Propionate in Human Plasma by High Performance Liquid Chromatography Atmospheric Pressure Chemical Ionization Mass Spectrometry Yan N.Li, Bruce N Tattam, Kenneth H Brown & John P Seale Presented at The Australasian Pharmaceutical Science Association (APSA) Scientific Meeting, 5-7 December 1996 in Melbourne. P64
1995
The analysis of drugs in saliva of drivers by Gas Chromatography Mass Spectrometry/Mass Spectrometry (GCMS/MS) utilising SRM. Bruce Tattam, Radek Zeleny, Graham Starmer, David Mascord. Presented at the 15th Conference of the Australian and New Zealand Society for Mass Spectrometry ANZSMS. UNSW September 1995. TuO-7
Determination of epimers 22R and 22S of Budesonide in human plasma by High Performance Liquid Chromatography / Atmospheric Pressure Chemical Ionization Mass Spectrometry. Benny Li, Bruce Tattam, Kenneth F Brown, Paul J. Seale. Australisian Society of Clinical & Experimental Pharmacologists and Toxicologists (ASCEPT, Adelaide December 1995)
Posters
2003
An APCI -LC-MS/MS Method For The Rapid Quantitative Analysis Of Ten Phytoestrogens In Human Urine
Bruce N Tattam, Tam C Ha & Douglas E Moore. Presented at the 19th Conference of the Australian and New Zealand Society for Mass Spectrometry ANZSMS . Lorne Vic February 2nd to 6th 2003. MonP-21
2002
Structural Determination of Major Degradation and Metabolic Products of Mometasone Furoate
XW. Teng. HTA. Cheung. DJ.Cutler, NM.Davies, BN.Tattam. To be Presented at the 5th Canadian Society for Pharmaceutical Sciences (CSPS) symposium in June 13-15, 2002 Banff, Canada
2000
Distribution of Tacrolimus In Human Blood.
H.Zahir, RA Nand, AJ McLachlan, BN Tattam & KF Brown. Presented at the Australasian Pharmaceutical Science Association ( APSA ) Newcastle NSW, Australia 6th - 8th December 2000 Poster Session B 88
1999
A Comparative Study Of Blood And Saliva With Analysis By GCMS/MS For The Analysis Of Ephedrine In Potential Road Users. Bruce Tattam, Graham Starmer and David Mascord. Presented at the 17th Australian and New Zealand Society for Mass Spectrometry Conference (ANZSMS 17) Thredbo Alpine Village,31st January to 4th February , 1999. WeP-12
GC/MS/MS Analysis Of Urinary Metabolites Of Organophosphorus Pesticides. Alex Oglobline, Helen Elimelakh, Bruce Tattam and Gerald Holder. Presented at the 17th Australian and New Zealand Society for Mass Spectrometry Conference (ANZSMS 17) Thredbo Alpine Village,31st January to 4th February , 1999. WeP-16
1997
Isolation Of Avermectins By Preperative HPLC With Following Identification Of Purified Components By HPLC/MS. Helen Elimelakh, Bruce Tattam, Colin Duke and Kay Lau. Presented at the 16th Conference of the Australian and New Zealand Society for Mass Spectrometry. (ANZSMS) February 3 to 6 1997 Hobart, University of Tasmania. TuP-02
1996
In Vivo Formation of Ibuprofen Cholesterol Esters. Carolyn J. Nelson, Brownyn A.Ellis,Franzi Lohrer,Bruce Tattam, Richard O.Day & Ken M. Williams. Presented at the 44th ASMS Conference on Mass Spectrometry and Allied Topics. Portland, Oregan, USA May 12-16 1996.
Identification and Characterization of Degradation Products of Beclomethasone Dipropionate in Human Plasma. Kuncoro Foe, Andrew Cheung, Bruce Tattam, Kenneth F Brown and John P Seale. Presented at The Australasian Pharmaceutical Science Association (APSA) Scientific Meeting, 5-7 December 1996 in Melbourne. P63
Technical Reports
1992
The effects of single acute therapeutic doses of Diazepam, alone and in combination with alcohol, on human performance in tests which examine aspects of driving ability:Relationships between performance decrements and blood concentrations of Diazepam and Alcohol. G.A.Starmer, D.J.Mascord, B.Tattam, J.H.Vine, T.R.Watson. Consultant Report CR 6/92 Roads and Traffic Authority. Road Safety Bureau.
The effects of Diazepam and Diazepam/Alcohol challenge on the performance in tests which examine aspects of driving ability of subjects who have been sub-chronically treated with a therapeutic dose of Diazepam. G.A.Starmer, D.J.Mascord, B.Tattam, J.H.Vine, T.R.Watson. Consultant Report CR 7/92 Roads and Traffic Authority. Road Safety Bureau.
1993
The effects of single acute therapeutic doses of Pentobarbitone, alone and in combination with alcohol, on human performance in tests which examine aspects of driving ability:Exploration of the relationships between performance decrements and blood concentrations of Pentobarbitone and Alcohol. G.A.Starmer, D.J.Mascord, B.Tattam, J.H.Vine, T.R.Watson. Consultant Report CR 2/93 Roads and Traffic Authority. Road Safety Bureau.
The effects of challenge with Pentobarbitone and Pentobarbitone/Alcohol on the performance in tests which examine aspects of driving ability of subjects who have received sub-chronic doses of Pentobarbitone. G.A.Starmer, D.J.Mascord, B.Tattam, J.H.Vine, T.R.Watson. Consultant Report CR 7/93 Roads and Traffic Authority. Road Safety Bureau.
1994
The effects of single acute therapeutic doses of Dexchlorpheniramine, alone and in combination with alcohol, on human performance in driving related tests:Exploration of the relationships between performance impairment and blood concentrations of Dexchlorpheniramine and Alcohol. G.A.Starmer, D.J.Mascord, B.Tattam, J.H.Vine, T.R.Watson. Consultant Report CR 1/94 Roads and Traffic Authority. Road Safety Bureau.
The effects of Dexchlorphenarmine/Alcohol challenge on the performance of subjects who had received the Anti-Histamine Dexchlorpheniramine Subchronically in tests which examine aspects of driving ability. G.A.Starmer, D.J.Mascord, B.Tattam, J.H.Vine, T.R.Watson. Consultant Report CR 2/94 Roads and Traffic Authority. Road Safety Bureau.
Analysis of Drugs in Saliva. Graham A Starmer, David Mascord, Bruce Tattam, Radek Zeleny Consultant Report CR 141 1994 For Reark Research & the Federal office of Road Safety.